lARe MONOGRAPHS PROGRAMME ON THE EVALUATION OF eARelNOGENie RISKS TO HUMANS'

ln 1969, the International Agency for Research on Cancer (lARe) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to incIude consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and of exposures to other agents, such as radiation and viruses. With Supplement 6 (lARC, 1987a), the title of the series was modified from lARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans to IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, in order to reflect the widened scope of the programme. The criteria established in 1971 to evaluate carcinogenic risk to humans were adopted by the working groups whose deliberations resulted in the first 16 volumes of the lARC Monographs series. Those criteria were subsequently updated by further ad-hoc working groups (IARC, 1977, 1978, 1979,1982, 1983, 1987b, 1988, 1991a; Vainio et aL., 1992).